Prescription CBD vape liquid (Passion Fruit) value Drug Information

CBD Passion Fruit Vape Liquid is in a 10 ml childproof bottle containing 500gm of pure CBD. It is diacetyl, alcohol-free and has no animal extracts. Cannabidiol (CBD) is one of the non-psychotropic cannabinoid derivatives of industrial hemp. It not only has a plethora of beneficial health effects, it also shows no relevant side-effects. CBD-containing extracts are increasingly used in food supplement compositions, and in its pure form, CBD is becoming a recognized application in assisting the treatment of medical conditions For different doses and applications of CBD-containing products, the European Industrial Hemp Association (EIHA) proposes a three-tier regulation: At high doses, CBD is a medicinal product and should be regulated as such. At medium doses, CBD-containing products should be regarded as an OTC-product (= over the counter) or a food supplement. This approach is already applied for many substances, such as valerian, glucosamine, chondroitin(sulfate), Ginkgo Biloba, some vitamins and iron products. Low CBD concentrations and doses should be allowed in food products without any restrictions. Additional aspects such as route of administration, indication area, maximum single / daily dose and pack size can be used to further fine-tune the assistance of a medical condition. It is generally recognized by CBD researchers that the minimum dosage for CBD to be effective in assisting the treatment of a medical condition is 5% w/v CBD being 500mg CBD in 10ml liquid. Why Vaping CBD is the best way to ingest it The oral bioavailability of CBD is roughly 15 percent. That means for every 100 milligrams of CBD that you eat,drink or put under your tongue, only 15 milligrams will actually reach your bloodstream.There are two main reasons why this happens. First, CBD is hydrophobic, meaning that it is not very water-soluble. In the same way that oil does not like to mix with vinegar, CBD does not like to stay in your bloodstream. Instead, it rapidly diffuses out of your blood and accumulates into your fatty tissues. Unfortunately, this significantly reduces the amount of bioactive CBD that can enter your systemic circulation, allowing for less CBD to be carried to its active sites in your body and thus lowering its overall bioavailability. Second, when an organic compound like CBD enters your gut, it has to pass through the liver before it enters your circulation. During this transition, the liver will actively reduce the amount of CBD, either through absorption or through chemical breakdown by liver enzymes. This phenomenon is called the, first-pass effect, where passing through the liver reduces the concentration of bioactive compounds. How to Offset CBD Loss by Vaporizing There are a few different ways to offset these losses of CBD. For one, you can reduce the amount of CBD that dissolves out of your bloodstream by putting the CBD into a form that is more hydrophilic,or water-soluble. However, this can only be achieved by complicated chemical means, such as through the use of cyclodextrins or liposomes. A more practical solution is to bypass the first-pass effect of oral administration entirely by utilizing vaporization. During vaporization, CBD enters your lungs and diffuses directly into your bloodstream rather than passing through your gut and liver. This avoids the first-pass effect altogether, allowing nearly four times as much CBD to enter your circulation for a maximum bioavailability of roughly 50 to 60 percent (4 X times oral ingestion). Essentially, this means, through vaping CBD, that you can achieve the same beneficial effects with a much smaller amount of CBD.